
Rabid
Bill Wasik and Monica Murphy
What's inside?
Explore the terrifying history and global impact of the deadly rabies virus, its influence on society, and the ongoing scientific quest to conquer it.
You'll learn
Key points
01The Birth of a Monster: The Origin of Rabies
The origin of the rabies virus, a deadly disease that has haunted humanity for centuries, can be traced back to the ancient city of Eshnunna, located in modern-day Iraq. The first recorded instance of the disease, dating back to 2300 B.C., was found inscribed on a cuneiform tablet. The description of the symptoms, including fever, headache, excess salivation, muscle spasms, paralysis, and mental confusion, mirrors the terrifying manifestations of rabies we know today. The fear of this disease was so profound in ancient times that it influenced the creation of laws. In Eshnunna, a law was enacted that held dog owners financially responsible if their dog bit a man, and the man subsequently fell ill and died. This law reflects the early understanding of the disease's transmission and the desperate attempts to control its spread. The journey to comprehend and combat the rabies virus was a long and arduous one. The ancient Greek physician Hippocrates, often referred to as the father of medicine, made significant observations about the disease. He noted that those bitten by a rabid dog often developed similar symptoms, a crucial insight into the transmission of the virus. However, it wasn't until the 19th century that a significant breakthrough was achieved. The French scientist Louis Pasteur developed the first successful rabies vaccine, a monumental step in the fight against this deadly virus. Pasteur's daring decision to test the vaccine on a nine-year-old boy bitten by a rabid dog marked a turning point in medical history. The cultural impact of rabies is as profound as its medical implications. The fear of the disease has permeated literature and folklore, influencing the creation of myths and narratives. The symptoms of rabies, including aggression, foaming at the mouth, and a fear of water, bear a striking resemblance to the characteristics often attributed to werewolves. This connection suggests that the myth of the werewolf may have been born out of the fear and misunderstanding of this terrifying disease. Rabies has also found its way into literature, serving as a symbol of fear and danger. The rabid dog in Harper Lee's "To Kill a Mockingbird" and the rabies-infected Cujo in Stephen King's novel of the same name are prime examples of how the fear of rabies has been used to create tension and terror in storytelling. In conclusion, the rabies virus, with its ancient origins and terrifying symptoms, has left a significant mark on human history. Its influence extends beyond the realm of medicine, shaping laws, myths, and literature. The journey to understand and combat this disease is a testament to human resilience and scientific progress. The story of rabies is not just a tale of a deadly virus, but also a reflection of humanity's enduring struggle against the unknown.
02The Dark Ages: Rabies in Medieval Times
In the Middle Ages, a period often characterized by superstition and fear of the unknown, the rabies virus emerged as a formidable and terrifying force. Its unpredictable spread and gruesome symptoms led to widespread fear and misunderstanding, with the virus often being associated with supernatural creatures prevalent in the folklore of the time. The aggressive behavior and hypersensitivity to stimuli exhibited by those infected with the virus mirrored the traits of mythical creatures such as werewolves and vampires, further fueling the fear and confusion. The 13th-century town of Metz in France provides a stark illustration of this fear and misunderstanding. When a rabid dog bit several townspeople, leading to a widespread outbreak of the disease, the townsfolk, lacking understanding of the virus, attributed the outbreak to a werewolf. This belief led to mass panic and a hunt for the supposed creature, exacerbating the fear and chaos in the town. The incident in Metz underscores the profound impact of the rabies virus on medieval societies, not only in terms of physical health but also in terms of psychological and social disruption. In a similar vein, the case of John Porter in 16th-century England further highlights the fear and misunderstanding surrounding the rabies virus. After being bitten by a rabid dog, Porter began to exhibit symptoms of the disease, including aggression, hallucinations, and a fear of water. The local populace, steeped in the folklore of vampires, believed that Porter had been turned into a vampire. This belief was reinforced when Porter, in his delirium, bit several other people, who then also began to show symptoms of the disease. The Porter incident demonstrates how the rabies virus, coupled with a lack of medical knowledge, could lead to the reinforcement of myths and unnecessary panic. These historical events underscore the significant influence of the rabies virus during the Middle Ages. The lack of medical knowledge about the disease led to its association with supernatural creatures, perpetuating myths and leading to unnecessary panic and chaos. The rabies virus, therefore, played a significant role in shaping societal perceptions and responses to disease during this period. It served as a catalyst for fear and misunderstanding, highlighting the dire need for scientific understanding and medical advancement. The history of rabies in the Middle Ages is a stark reminder of the power of fear and the importance of knowledge in combating disease.

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03The Enlightenment: Scientific Understanding of Rabies
04The Global Spread: Rabies in the New World
05Modern Times: Rabies in the 20th Century
06The Future: Rabies in the 21st Century and Beyond
07Conclusion
About Bill Wasik and Monica Murphy
Bill Wasik is a senior editor at Wired and former editor at Harper's Magazine. Monica Murphy is a veterinarian with a degree in public health. They co-authored "Rabid: A Cultural History of the World's Most Diabolical Virus," combining their expertise in journalism and health science.